Mission-driven science

Turning research advances into better therapies for patients with advanced cancers.

Pioneering company

Using the right team with the right resources to address many of cancer’s toughest challenges.

triumph over cancer

We strive to meet the challenges of advanced cancers through combination therapies.

First-in-Class

Medicine

First-in-class small molecules that disable adaptive responses in many types of cancer

OncoSpherix’s lead compounds disrupt the activation of HIFs by preventing the recruitment of the transcriptional co-activator paralogs p300/CBP to the nascent transcription complex by binding to the CH-1 domain of p300/CBP.

Are you ready to Learn More?

We’re planning clinical trials of agents designed to improve quality of life and survival in patients with a variety of advanced cancers.